Background The regulatory requirements for approval of generic medicines and the format of compiling drug dossiers vary among regulatory authorities.The variation is particularly wide between High-income countries (HIC) and lower and middle-income countries (LMIC) with different regulatory frameworks.In this study, document requirements for approva

Background: It has been demonstrated that exosomes derived from HPV-16 E7-over-expressiong non-small cell lung cancer (NSCLC) cells (E7 Exo) trigger increased levels of epidermal growth factor receptor (EGFR) and miR-381-3p.The purpose of this investigation was to examine the role of E7 Exo in NSCLC angiogenesis, and to analyze the contribution of

Rising income inequality has recently garnered intensive attention owing to its significance in theory and practice.This has rendered the mechanism through Paddock Boots which inequality can be understood, even from a microscopic perspective, to institute proper policies that curtail it important.We contribute to the literature by examining the eff

Histology is key to understand physiology, development, growth and even reproduction of extinct animals.However, the identification and interpretation of certain structures, such as osteons, medullary bone (MB), and Lines of Arrested Growth (LAGs), are not only based on personal judgments, but also require considerable labor for subsequent analysis

[Objective] To address the significant challenges posed by global economic development and intensified human activities to fragile ecosystems, this study systematically synthesized and comparatively characterized regional soil erosion control technologies (SECTs).The aim was to prevent, mitigate, and reverse soil erosion trends, while providing a r